Urolithin A 99% GRAS certificated Ingredients for Brain Health
Product Name: Urolithin A
Synonym Name: 3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one
CAS. Number: 1143-70-0
Molecular weight: C13H8O4
Specifications: Urolithin A 99%
Appearance: Beige to light yellow powder
Urolithin A
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Urolithin A introduction
Urolithin A, also called 3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one contains NLT 98.0% of Urolithin A (C13H8O4), calculated on the anhydrous basis. It’s a secondary metabolite of ellagic acid, a polyphenolic antioxidant that has anti-proliferative, anti-inflammatory,and anti-oxidant properties.
Urolithin A mapping 1
Urolithin A mapping 2
Benefits of Urolithin A
❶ Urolithin A decreases proliferation in ECC-1, and modulates estrogen receptor-regulated gene expression..
❷ Urolithin A reduces inflammation and decreasing prostagelandine E2 and preventing protein levels in colonic mucosa.
❸ Urolithin A induces mitophagy and mode-K intestinal cells in correlation withi improved fitness and extended lifespan.
Typical specification sheet of Urolithin A 99%
| Analysis Items | Specifications | Methods |
| Identifications | ||
| 1H NMR confirms to product structure. | |
| LC-MS Conforms to molecular weight. | |
| Retention time of the sample matches with the RS in HPLC purity test. | |
| Physical Tests | ||
| Appearance | Beige to light yellow powder | Visual |
| Melting point | 65~67℃ | GB 617 |
| Bulk density | 0.30-0.60g/mL | GB 5009.2 |
| Moisture content | ≤0.50% | GB 5009.3 |
| Residue on ignition | ≤0.50% | GB 5009.4 |
| Active Ingredients Tests | ||
| Urolithin A Purity | ≥98.00% | HPLC |
| Max Single impurity | ≤1.00% | HPLC |
| Chemical Tests | ||
| Heavy Metals | ≤10.00ppm | GB 5009.74 |
| Pb<Lead> | ≤3.00ppm | GB 5009.12 |
| As<Inorganic arsenic> | ≤2.00ppm | GB 5009.11 |
| Cd<Cadmium> | ≤1.00ppm | GB 5009.15 |
| Hg<Total mercury> | ≤0.10ppm | GB 5009.17 |
| Residue of Methanol | ≤3,000ppm | GB 5009.262 |
| Residue of DMSO | ≤5,000ppm | GB 5009.262 |
| Residue of Acetic Acid | ≤5,000ppm | GB 5009.262 |
| Microbiological Tests | ||
| Total Bacterial Counts | ≤1,000cfu/g | GB 4789.2 |
| Yeasts and Molds | ≤100cfu/g | GB 4789.15 |
| Coliform group | ≤1.0MPN/g | GB 4789.3 |
| Salmonella | Negative in 10g | GB 4789.4 |
| * Conclusion: Conform to above specifications. | ||
| * Packaging: 20/25kg per fiber drum. | ||
| * Storage Condition: Preserve in well-closed, tight containers with temperature below 10℃. | ||
| * Shelf Life: 3 years when properly stored. | ||
Application Cases
